Cabergoline is a white powder soluble in ethyl alcohol, chloroform, and N, N- dimethylformamide (DMF); slightly soluble in 0.1N hydrochloric acid; very slightly soluble in n-hexane; and insoluble in water.
Cabaser (cabergoline) for oral administration, contain 1 mg of cabergoline. Inactive ingredients consist of leucine, USP, and lactose, NF.

Ongoing review of clinical studies suggests that fibrosis and valvulopathy are associated with ergot-derived dopamine agonists, including Cabaser (cabergoline) and could be linked to cumulative doses of the medicine.

Product Physician, Dr Louise Canny explained that as a result of these studies Pfizer Australia has decided to reduce the maximum daily dose of Cabaser (cabergoline) from 6mg per day to 3 mg per day. "It is anticipated that the reduction in the recommended maximum daily dose of Cabaser along with the current recommendations for assessment of patients prior to commencing therapy and during maintenance therapy included in the Cabaser (cabergoline)Product Information, should help reduce the risk of fibrotic reactions," explained Dr Canny.
These changes do not affect the availability of Cabaser 1mg and 2mg tablets which will continue to be available through the Pharmaceutical Benefits Scheme (PBS).

USAGE:

Cabaser (cabergoline) is usually taken twice each week for at least 6 months. Do not take this medication every day unless your doctor tells you to.
To be sure this medication is helping your condition, your blood will need to be tested on a regular basis to measure your prolactin levels. Your doctor may want to continue checking your prolactin levels for several months after you stop taking Cabaser (cabergoline). Do not miss any scheduled visits.
Store Cabaser (cabergoline) at room temperature away from moisture and heat.

SIDE EFFECTS:

Get emergency medical help if you have any of these signs of an allergic reaction: hives, difficulty breathing, swelling of your face, lips, tongue, or throat. Stop using cabergoline and call your doctor at once if you have any of these serious side effects:
-cough or trouble breathing
-feeling light-headed, fainting

Less serious side effects may include:
-nausea, vomiting, stomach pain, constipation
- headache
-dizziness, drowsiness, nervousness
-numbness or tingly feeling
- hot flashes

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.